Young nephron progenitors might extend the lifespan of old progenitors
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چکیده
منابع مشابه
Sall1 in renal stromal progenitors non-cell autonomously restricts the excessive expansion of nephron progenitors
The mammalian kidney develops from reciprocal interactions between the metanephric mesenchyme and ureteric bud, the former of which contains nephron progenitors. The third lineage, the stroma, fills up the interstitial space and is derived from distinct progenitors that express the transcription factor Foxd1. We showed previously that deletion of the nuclear factor Sall1 in nephron progenitors ...
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ژورنال
عنوان ژورنال: Nature Reviews Nephrology
سال: 2015
ISSN: 1759-5061,1759-507X
DOI: 10.1038/nrneph.2015.179